| Property |
Value |
| Working Groups |
RG Cantuti-Castelvetri, 
RG Gokce, 
RG Simons, 
RG Stadelmann-Nessler |
| Subproject |
A06 |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
33082293 |
| DOI |
10.1126/science.abd2985 |
| Publication Year |
2020 |
| Title |
Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity.
|
| Journal |
Science |
| ISSN |
0036-8075 |
| eISSN |
1095-9203 |
| URL |
https://www.ncbi.nlm.nih.gov/pubmed/?term=33082293%5Buid%5D |
| Pages |
856-860 |
| Issue |
6518 |
| Volume |
370 |
| Journal Abbreviation |
Science |
| Authors |
Cantuti-Castelvetri L, Ojha R, Pedro LD, Djannatian M, Franz J, Kuivanen S, van der Meer F, Kallio K, Kaya T, Anastasina M, Smura T, Levanov L, Szirovicza L, Tobi A, Kallio-Kokko H, Österlund P, Joensuu M, Meunier FA, Butcher SJ, Winkler MS, Mollenhauer B, Helenius A, Gokce O, Teesalu T, Hepojoki J, Vapalahti O, Stadelmann C, Balistreri G, Simons M |
| First Author |
Cantuti-Castelvetri L |
| Last Author |
Simons M |
| Scholia |
Wikidata-based representation at Scholia |
External Resources
1786https://www.addgene.org/1786 Addgene identifier (1786, reused)
github.c...NA-seqhttps://github.com/vandijklab/HBEC_SARS-CoV-2_scRNA-seq Dataset (Differentially expressed genes table, reused)
figshare...235471https://figshare.com/articles/HCL_DGE_Data/7235471 Dataset (Human lung data, reused)
gro-2/83594http://resolver.sub.uni-goettingen.de/purl?gro-2%2F83594= GRO.publications identifier
GSE139522https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE139522 NCBI GEO Dataset (GSE139522, reused)
GSE145926https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE145926 NCBI GEO Dataset (GSE145926, reused)
NC_045512.2https://www.ncbi.nlm.nih.gov/nuccore/NC_045512.2 NCBI nucleotide (NC_045512.2)
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
10090https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 NCBI Taxonomy (mouse, Mus musculus)
0000-0002-0642-1610https://orcid.org/0000-0002-0642-1610 ORCID identifier (Ludovico Cantuti-Castelvetri)
0000-0001-7876-4607https://orcid.org/0000-0001-7876-4607 ORCID identifier (Ravi Kant Ojha)
0000-0002-7759-6557https://orcid.org/0000-0002-7759-6557 ORCID identifier (Minou Djannatian)
0000-0003-3556-647Xhttps://orcid.org/0000-0003-3556-647X ORCID identifier (Liliana D. Pedro)
0000-0002-2347-5397https://orcid.org/0000-0002-2347-5397 ORCID identifier (Suvi Kuivanen)
0000-0001-7523-6622https://orcid.org/0000-0001-7523-6622 ORCID identifier (Jonas Franz)
0000-0002-9433-9173https://orcid.org/0000-0002-9433-9173 ORCID identifier (Franziska van der Meer)
0000-0001-5926-8608https://orcid.org/0000-0001-5926-8608 ORCID identifier (Tugberk Kaya)
0000-0002-4555-6446https://orcid.org/0000-0002-4555-6446 ORCID identifier (Maria Anastasina)
0000-0003-1528-044Xhttps://orcid.org/0000-0003-1528-044X ORCID identifier (Leonora Szirovicza)
0000-0003-4797-5481https://orcid.org/0000-0003-4797-5481 ORCID identifier (Allan Tobi)
0000-0002-2229-6661https://orcid.org/0000-0002-2229-6661 ORCID identifier (Pamela Österlund)
0000-0002-4533-0455https://orcid.org/0000-0002-4533-0455 ORCID identifier (Merja Joensuu)
0000-0001-6400-1107https://orcid.org/0000-0001-6400-1107 ORCID identifier (Frederic A. Meunier)
0000-0001-7060-5871https://orcid.org/0000-0001-7060-5871 ORCID identifier (Sarah Jane Butcher)
0000-0001-6319-404Xhttps://orcid.org/0000-0001-6319-404X ORCID identifier (Özgün Gökçe)
0000-0002-9458-6385https://orcid.org/0000-0002-9458-6385 ORCID identifier (Tambet Teesalu)
0000-0001-5699-214Xhttps://orcid.org/0000-0001-5699-214X ORCID identifier (Jussi Hepojoki)
0000-0003-2270-6824https://orcid.org/0000-0003-2270-6824 ORCID identifier (Olli Pekka Vapalahti)
0000-0003-1766-5458https://orcid.org/0000-0003-1766-5458 ORCID identifier (Christine Stadelmann-Nessler)
0000-0002-3585-559Xhttps://orcid.org/0000-0002-3585-559X ORCID identifier (Giuseppe Balistreri)
0000-0001-5329-192Xhttps://orcid.org/0000-0001-5329-192X ORCID identifier (Mikael Jakob Simons)
73https://prod.mbexc.uni-goettingen.de/literature/publications/73 Published Data Registry entry (MBExC)
2/9https://rdp.sfb274.de/archive/2/9 Research Data Archive (supplemental material)
043j0f473https://ror.org/043j0f473 ROR identifier (043j0f473, German Center for Neurodegenerative Diseases)
05591te55https://ror.org/05591te55 ROR identifier (05591te55, Ludwig-Maximilians-Universität München)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
02kkvpp62https://ror.org/02kkvpp62 ROR identifier (02kkvpp62, Technical University of Munich)
CVCL_0025https://scicrunch.org/resolver/CVCL_0025 SciCrunch identifier (RRID:CVCL_0025, Caco-2)
CVCL_0045https://scicrunch.org/resolver/CVCL_0045 SciCrunch identifier (RRID:CVCL_0045, HEK293)
SCR_007358https://scicrunch.org/resolver/SCR_007358 SciCrunch identifier (RRID:SCR_007358, CellProfiler)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_002630https://scicrunch.org/resolver/SCR_002630 SciCrunch identifier (RRID:SCR_002630, GitHub)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)
SCR_014479https://scicrunch.org/resolver/SCR_014479 SciCrunch identifier (RRID:SCR_014479, Inkscape)
SCR_014551https://scicrunch.org/resolver/SCR_014551 SciCrunch identifier (RRID:SCR_014551, Olympus cellSens Software)
SCR_002629https://scicrunch.org/resolver/SCR_002629 SciCrunch identifier (RRID:SCR_002629, OMERO)
SCR_002105https://scicrunch.org/resolver/SCR_002105 SciCrunch identifier (RRID:SCR_002105, Samtools)
SCR_007322https://scicrunch.org/resolver/SCR_007322 SciCrunch identifier (RRID:SCR_007322, Seurat)
SCR_011848https://scicrunch.org/resolver/SCR_011848 SciCrunch identifier (RRID:SCR_011848, Trimmomatic)
science....sm.pdfhttps://www.science.org/doi/suppl/10.1126/science.abd2985/suppl_file/abd2985_cantuti-castelvetri_sm.pdf Supplemental material
science....st.pdfhttps://www.science.org/doi/suppl/10.1126/science.abd2985/suppl_file/abd2985_mdar_reproducibility_checklist.pdf Supplemental material (reproducibility checklist)
en.bio-p...bd2985https://en.bio-protocol.org/cjrap.aspx?eid=10.1126/science.abd2985 Supplemental material (protocol on request at bio-protocol.org)
Q100750024https://www.wikidata.org/wiki/Q100750024 Wikidata ID
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0001 |
|
primary |
NRP1 |
AB_1640739 |
anti-neuropilin-1 |
| primary-0002 |
|
primary |
NeuN |
AB_11205760 |
Anti-NeuN Antibody |
| primary-0003 |
|
primary |
|
AB_221570 |
GFP Polyclonal Antibody |
| primary-0004 |
|
primary |
COL4A1 |
AB_2721907 |
Goat Anti-Type IV Collagen-UNLB |
| primary-0005 |
|
primary |
PECAM1 |
AB_2801330 |
PECAM-1 Antikörper (H-3) |
| primary-0006 |
|
primary |
AQP4 |
AB_2039734 |
Anti-Aquaporin 4 (AQP4) (249-323) Antibody |
| primary-0007 |
|
primary |
ACE2 |
AB_355722 |
Human/Mouse/Rat/Hamster ACE-2 Antibody |
| primary-0008 |
|
primary |
NRP1 |
AB_2282634 |
neuropilin Antikörper (A-12) |
| primary-0009 |
|
primary |
|
|
Anti-SARS spike glycoprotein antibody [3A2] - Coronavirus |
| primary-0010 |
|
primary |
OLIG2 |
AB_494617 |
OLIG2 anti-human rabbit IgG affinity purify |
| primary-0011 |
|
primary |
|
|
SARS-CoV-2 (2019-nCoV) Spike RBD Antibody, Rabbit PAb, Antigen Affinity Purified |
| primary-0012 |
|
primary |
TUBA1A |
AB_301787 |
Anti-alpha Tubulin antibody - Microtubule Marker |
| secondary-0014 |
|
secondary |
|
AB_2556542 |
Donkey anti-Mouse IgG (H+L) ReadyProbes™ Secondary Antibody, Alexa Fluor 488 |
| secondary-0015 |
|
secondary |
|
AB_2535849 |
Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 555 |
| secondary-0016 |
|
secondary |
|
AB_2534096 |
Goat anti-Chicken IgY (H+L) Secondary Antibody, Alexa Fluor 488 |
| secondary-0017 |
|
secondary |
|
AB_2340430 |
Alexa Fluor® 488 donkey anti-goat |
| secondary-0018 |
|
secondary |
|
AB_2535853 |
Donkey anti-Goat IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 555 |
| secondary-0019 |
|
secondary |
|
AB_2535844 |
Goat anti-Mouse IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 555 |
| secondary-0020 |
|
secondary |
|
AB_2536183 |
Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 647 |
| secondary-0021 |
|
secondary |
|
AB_1082105 |
Donkey Anti-Sheep Immunoglobulin Polyclonal, Biotin Conjugated antibody |
| secondary-0022 |
|
secondary |
|
AB_1062579 |
Anti-Mouse Ig (Whole Ab) Antibody, Biotin Conjugated |